Want to see the best of Mississippi history? Add these four destinations’ historic sites to your Mississippi road trip itinerary.

© Rory Doyle
Clarksdale
The Home of Blues, aka Clarksdale, was founded in 1848 and is now your spot to learn not just about the history of blues, but also the history of the Delta region. Stop into two museums during your road trip: Delta Blues Museum and North Delta Museum.
Natchez
Natchez is the oldest continuous European settlement on the Mississippi River. Before the Europeans arrived in the 1700s, though, the Natchez indigenous peoples called the region home. Now, the city shows off its indigenous, African, French, British and Spanish heritage with pride.

Quapaw River © Rory Doyle
Oxford
Oxford has become known as a destination for college football thanks to the University of Mississippi, but it also boasts a lot of literary history. The most famous historical literary site is likely Rowan Oak, William Faulkner’s home, but you can also plan an entire Oxford literary itinerary to see even more.
Tupelo
Lastly, Tupelo gets recognition for its role in the Civil War, as well as for being the birthplace of Elvis Presley. To learn more about both, visit Tupelo National Battlefield site and take Elvis’s Tupelo Driving Tour.
Read This Next
#TrazeeTravel
Insta FeedHotel
Oct 8, 2026Kimpton Ashbel Introduces Picnic on the Park Escape
Kimpton Ashbel New York-Park Avenue introduces Picnic on the Park Escape, an experience for guests to enjoy an afternoon outdoors in the cool, fall air.
Sponsored Content
GET TO KNOW TAP FORBIZ
Unlock flexible, refined business travel with TAP Air Portugal’s program, TAP FORBIZ. Developed for small, medium and large Companies, with options for corporate events, TAP FORBIZ offers exclusive advantages adapted to each type of business.
Dining/Entertainment
Oct 8, 2026Fourth Annual Mexology Fest Coming to Riviera Nayarit
Make plans for the Nov. 2–3 Mexology Fest at Grand Velas Riviera Nayarit. The celebration blends Day of the Dead traditions and Mexican spirits, with resort guests enjoying tasting, workshops and more, for four years and counting.
Hotel
Oct 7, 2026Hyatt Vivid Cancun Ushers in New Era of Social Travel
Wellness tourism continues to grow, and more and more tropical resorts shy away from traditional amenities like swim-up bars, late-night activities and traditional happy hours, instead opting for more immersive and community-driven experiences. A new kind of resort travel is emerging where connection, movement and shared experiences take center stage.
Sponsored Content
An Adults-Only Resort for All the Milestone Moments
On Saturday, Feb.14, Devossion by Live Aqua celebrated its grand opening, marking a significant milestone for Grupo Posadas and the Live Aqua brand. This adults-only resort focuses on celebration, authentic Mexican experiences and elevated hospitality — perfectly situated in the heart of the Riviera Maya.
Destinations
Oct 7, 20265 Spine-Tingling Adventure Destinations from Wild Frontiers
Just in time for spooky season, Wild Frontiers reveals five extraordinary and spine-tingling adventure destinations.
ShareThis